In this edition of our newsletter, we present the concept of “Sustainable Knowledge".

As it is an intervention with significant adverse effects and elevated costs, it does not seem like a reasonable option at present, although it has been used for many years for the treatment of various infectious or autoimmune diseases.

To understand the arguments behind each of the suggestions that have been circulating, it is necessary to understand the concepts of direct evidence, indirect evidence, preliminary evidence, systematic reviews, certainty of evidence, and publication bias.